Testosterone Replacement Therapy — Physician-Supervised Injections Shipped to Your Door
Pure IV offers physician-supervised testosterone cypionate injections for men with clinically confirmed low testosterone. Every patient completes required lab work and a licensed provider consultation before any prescription is written. No exceptions.
$199 Per Month
What Is Testosterone Replacement Therapy?
Testosterone is a hormone your body produces naturally. It plays a key role in muscle mass, bone density, red blood cell production, fat distribution, mood, energy levels, and sexual function. As men age, testosterone levels naturally decline — typically about 1% per year after age 30.
Low testosterone (also called hypogonadism or “low T”) occurs when the body does not produce enough testosterone on its own. Symptoms can include persistent fatigue, reduced muscle mass, increased body fat, low libido, difficulty concentrating, irritability, and depressed mood.
Testosterone Replacement Therapy (TRT) is a medical treatment that restores testosterone levels to a healthy, normal range under the supervision of a licensed provider. TRT does not boost testosterone beyond normal levels — it replaces what your body is no longer producing adequately.
Pure IV prescribes TRT only after lab-confirmed low testosterone and a clinical evaluation by a licensed nurse practitioner. This is a medical treatment, not a supplement or a shortcut.
Product Details
Medication
- Active Ingredient: Testosterone Cypionate
- Drug Class: Androgen; Schedule III Controlled Substance (DEA)
- Route of Administration: Intramuscular (IM) injection, self-administered at home
- Carrier Oil: Grape seed oil or MCT oil (medium-chain triglyceride oil)
- Preservatives: May include benzyl alcohol and/or benzyl benzoate depending on compounding pharmacy formulation
Standard Starting Dosage
The standard starting dose for most patients is 75 mg to 100 mg, administered twice per week via intramuscular injection. Your prescribing provider will determine the appropriate starting dose based on your lab results, symptoms, age, and medical history.
Dosage may be adjusted at follow-up appointments based on repeat lab work and symptom response. Never adjust your dose without direction from your provider.
Benefits of Testosterone Replacement Therapy
When prescribed appropriately for clinically low testosterone, TRT may help with the following:
Increased Energy & Reduced Fatigue
Many men with low T report significant fatigue that does not improve with rest. Restoring testosterone to normal levels often improves overall energy and endurance.
Improved Muscle Mass & Strength:
Testosterone plays a direct role in muscle protein synthesis. TRT can support lean muscle development when combined with regular exercise.
Reduced Body Fat
Low testosterone is associated with increased abdominal fat. Healthy testosterone levels can support improved body composition over time.
Improved Mood & Mental Clarity
Low T is linked to irritability, difficulty concentrating, and depressed mood. Many patients report improved focus and emotional stability on TRT.
Restored Libido & Sexual Function
Testosterone is essential for healthy sexual function. TRT often improves sex drive and may help with erectile function in men with confirmed low T.
Better Sleep Quality
Some patients with low testosterone experience disrupted sleep patterns that improve with treatment.
Improved Bone Density
Testosterone supports bone mineral density. Long-term TRT may reduce the risk of osteoporosis in men with hypogonadism.
Important: Results vary by individual. TRT is not a performance-enhancing drug when prescribed at therapeutic doses. Pure IV prescribes TRT strictly to restore testosterone to normal physiological levels.
Who Is Eligible?
Testosterone replacement therapy is a prescription medical treatment. Not everyone qualifies. Pure IV requires the following before any prescription is written:
Required Lab Work
All patients must complete comprehensive blood work before a prescription is considered. Required labs include:
- Total Testosterone
- Free Testosterone
- Complete Blood Count (CBC) — including hematocrit and hemoglobin
- Comprehensive Metabolic Panel (CMP)
- Prostate-Specific Antigen (PSA) — for prostate cancer screening
- Estradiol (E2)
- Lipid Panel
Your provider may order additional labs based on your medical history and symptoms.
Clinical Criteria
- Lab-confirmed low testosterone levels
- Symptomatic presentation consistent with hypogonadism
- No contraindications identified during medical review (see Contraindications section below)
- Male patients 18 years of age or older
Pure IV does not prescribe testosterone without completed lab work reviewed and approved by a licensed prescribing provider. There are no exceptions to this policy.
Potential Side Effects
Like any prescription medication, testosterone cypionate may cause side effects. Most side effects are manageable and may resolve as your body adjusts to treatment. Your provider will monitor you throughout your treatment to minimize risks.
Common Side Effects
- Acne or oily skin
- Injection site soreness, redness, or swelling
- Mood changes, including irritability or increased aggression
- Fluid retention
- Increased red blood cell count (polycythemia)
- Changes in hair growth patterns (increased body hair or accelerated male-pattern hair loss)
Less Common but Serious Side Effects
- Elevated hematocrit (increased blood thickness) — monitored via regular CBC labs
- Testicular atrophy (shrinkage) with long-term use
- Reduced sperm production — TRT may impair fertility
- Elevated estrogen levels (estradiol) — may cause gynecomastia (breast tissue growth)
- Sleep apnea — may worsen in patients with existing sleep apnea
- Elevated liver enzymes (rare with injectable testosterone cypionate)
- Cardiovascular considerations — some studies suggest potential increased risk of cardiovascular events; your provider will evaluate your individual risk factors
If you experience chest pain, shortness of breath, swelling in your legs, severe headaches, or signs of an allergic reaction (hives, difficulty breathing, swelling of the face or throat), seek emergency medical attention immediately.
Contraindications — Who Should NOT Take Testosterone
Testosterone replacement therapy is not appropriate for everyone. TRT is contraindicated in patients with the following:
- Known or suspected prostate cancer
- Known or suspected breast cancer in men
- Uncontrolled congestive heart failure
- Elevated hematocrit (above the upper limit of normal prior to treatment)
- Severe untreated sleep apnea
- Active desire for fertility — TRT may significantly reduce sperm count
- Known hypersensitivity to testosterone cypionate or any component of the formulation (including carrier oils)
- Women who are pregnant or may become pregnant — testosterone can cause fetal harm
- Patients under 18 years of age
Your provider will review your full medical history and lab results to determine if TRT is safe and appropriate for you.
How It Works — Our Process
Pure IV makes testosterone replacement therapy accessible without sacrificing medical safety. Here is exactly how the process works:
Step 1
Book a Consultation
Call (833) 688-1299 or book online to schedule a telehealth consultation with a licensed nurse practitioner. During this initial consult, your provider will review your symptoms, medical history, current medications, and determine if you are a candidate for TRT.
Step 2
Complete Required Lab Work
Your provider will order comprehensive blood work. Labs can be completed at a local lab near you. No prescription is written until your lab results have been reviewed and confirm clinically low testosterone.
Step 3
Provider Review & Prescription
Your licensed nurse practitioner reviews your lab results and clinical evaluation. If you meet eligibility criteria, a prescription for testosterone cypionate is written at the appropriate dose for your needs. If you do not qualify, your provider will discuss alternative options or refer you to a specialist.
Step 4
Medication Shipped to Your Door
Your testosterone cypionate is shipped directly to your home. As a Schedule III controlled substance, all shipments comply with DEA regulations. Your shipment includes your medication vial, syringes, alcohol swabs, and injection instructions.
Step 5
Self-Administer at Home
You self-administer your prescribed dose via intramuscular injection at home, typically twice per week. Your provider will walk you through proper injection technique during your consultation. Used needles and syringes should be disposed of in an FDA-cleared sharps disposal container.
Step 6
Ongoing Monitoring & Follow-Up
Follow-up lab work is required every 6 to 8 weeks initially. After your levels stabilize, follow-up labs are required every 3 to 6 months depending on your provider’s assessment. Dose adjustments are made based on your lab results and symptom response. Your provider monitors hematocrit, testosterone levels, PSA, and other markers at every follow-up.
Ongoing Monitoring & Patient Safety
TRT is not a “set it and forget it” treatment. Responsible testosterone therapy requires ongoing medical monitoring. Pure IV takes this seriously.
What We Monitor
- Testosterone levels (total and free) — to ensure levels are within the therapeutic range, not above
- Hematocrit and hemoglobin (CBC) — elevated hematocrit is the most common safety concern with TRT and may require dose reduction or temporary discontinuation
- PSA (Prostate-Specific Antigen) — to screen for prostate changes
- Estradiol (E2) — testosterone can convert to estrogen; elevated levels may require intervention
- Liver function — as clinically indicated
- Lipid panel — to monitor cardiovascular risk factors
- Patient-reported symptoms — mood, energy, libido, side effects
When Dose Adjustments Are Made
Your provider may adjust your dose if your testosterone levels are outside the target range (too high or too low), if your hematocrit rises above safe thresholds, if you experience significant side effects, or if your symptom response indicates a change is needed. All dose changes are based on lab data and clinical judgment — never patient request alone.
Follow-Up Schedule
| Timeframe | Requirement |
|---|---|
| Initial Labs | Required before any prescription is written |
| 6–8 Weeks | First follow-up labs to assess response and safety markers |
| 3–6 Months | Ongoing follow-up labs once levels are stable |
| Annually | Comprehensive review including PSA, CBC, metabolic panel, and lipid panel |
FAQ's
Frequently Asked Questions
What are testosterone injections?
Testosterone injections are a form of testosterone replacement therapy (TRT) that delivers testosterone cypionate directly into the muscle via injection. This is the most common and well-studied method of TRT. The medication is self-administered at home on a schedule determined by your provider.
Who is eligible for testosterone replacement therapy?
Adult men (18+) with lab-confirmed low testosterone and symptoms consistent with hypogonadism may be eligible. All patients must complete required lab work and a telehealth consultation with a licensed nurse practitioner. Patients with certain medical conditions (see Contraindications) are not eligible.
Can I get testosterone without lab work?
No. Pure IV requires completed lab work reviewed by a licensed provider before any testosterone prescription is written. There are no exceptions to this policy. This is a medical and legal requirement for responsible prescribing of a controlled substance.
Are there side effects?
Yes. Common side effects include acne, injection site soreness, and mood changes such as irritability. Less common but more serious side effects include elevated hematocrit (blood thickening), testicular atrophy, reduced fertility, and potential cardiovascular considerations. Your provider monitors you with regular lab work to catch and manage side effects early. See the full Side Effects section above for details.
How is the testosterone shipped?
Testosterone cypionate is a Schedule III controlled substance and is shipped directly to you in compliance with all DEA shipping regulations. Your shipment includes the medication vial, syringes, alcohol swabs, and injection instructions. All shipments are discreet.
How do I inject testosterone at home?
Your provider will walk you through proper injection technique during your consultation. Testosterone cypionate is administered as an intramuscular (IM) injection, typically in the thigh (vastus lateralis) or glute (gluteus medius). You will self-inject your prescribed dose twice per week.
How often do I need follow-up lab work?
Follow-up labs are required every 6 to 8 weeks when you first start TRT. Once your levels stabilize and your provider is satisfied with your response, follow-ups move to every 3 to 6 months depending on your individual needs.
Will TRT affect my fertility?
TRT can significantly reduce sperm production and may impair fertility. If you are actively trying to conceive or plan to in the near future, discuss this with your provider before starting treatment. TRT is generally not recommended for men with an active desire for fertility.
Is testosterone replacement therapy safe?
When prescribed at appropriate therapeutic doses and monitored with regular lab work, TRT is a well-established medical treatment. Risks increase when testosterone is used without medical supervision, at supra-physiological doses, or without monitoring. Pure IV’s protocol includes mandatory lab work and ongoing provider oversight to ensure patient safety.
How do I dispose of used needles?
Used needles and syringes should be placed in an FDA-cleared sharps disposal container. Do not throw loose needles in the trash. If you do not have a sharps container, you can use a heavy-duty plastic household container (such as a laundry detergent bottle) with a tight-fitting, puncture-resistant lid. Contact your local waste management authority for sharps disposal locations near you.
Why Choose Pure IV for Testosterone Therapy
- Physician-Owned:
Pure IV is a physician-owned company, not a subscription mill. Your care is overseen by licensed medical professionals.
- Licensed Providers:
Every patient consults with a licensed nurse practitioner who reviews labs and determines eligibility.
- Lab Work Required — No Exceptions: We never prescribe testosterone without completed, reviewed lab work confirming clinical need.
- Ongoing Monitoring:
Regular follow-up labs are required to ensure your treatment remains safe and effective.
- 25,000+ Patients Served:
Pure IV has served over 25,000 patients across 10 markets in 8 states.
- Discreet Home Delivery:
Medication shipped directly to your door with everything you need to self-administer safely.
- HIPAA Compliant:
All patient information is protected and handled in full compliance with HIPAA regulations.
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