Mobile IV Therapy in

Knoxville, Tennessee

Professional IV hydration and wellness treatments delivered directly to you throughout Knoxville. We bring licensed nurses and premium IV therapy straight to your home, hotel, or workplace for fast, reliable care.

★★★★★ Trusted by 25,000+ of satisfied patients | HIPAA Compliant | Free Good Faith Exam | Licensed Tennessee Nurses | No Travel Fees | No Waiting Rooms | HSA & FSA Accepted

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Real-Time NP Approval
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Same-Day Availability
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No Travel Fee
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Registered Nurses &
Paramedics
A smiling person in black scrubs stands by an IV pole, chatting with two people receiving IV therapy in a home setting.

Knoxville’s Most Trusted Mobile IV Therapy Provider

Knoxville is one of the most active cities in East Tennessee. It is home to the University of Tennessee, a growing downtown scene, and the gateway to the Great Smoky Mountains. Whether you live here or you are visiting for a UT football game at Neyland Stadium, a weekend on the town along Gay Street, or a hike through the Smokies, your body needs to stay hydrated and fueled.


That is where Pure IV comes in. We deliver professional mobile IV therapy directly to your door anywhere in the Knoxville metro area. Our licensed Tennessee Registered Nurses bring hospital-grade IV treatments to your home, hotel room, Airbnb, office, or event space. You do not need to drive anywhere, sit in a waiting room, or leave your couch. We come to you, and we come fast with same-day service available seven days a week.


Pure IV is physician-owned and operated across 10 markets in 8 states. We are not a franchise. We are not a startup figuring things out. We are an experienced, medical-first IV therapy company that has served over 25,000 patients nationwide. Now we are bringing that same standard of care to Knoxville, Tennessee.

Why Knoxville Chooses Pure IV Over Other IV Therapy Companies

There are other IV therapy providers in Knoxville. Some are brick-and-mortar clinics. Some are mobile services. But none of them offer what Pure IV offers. Here is what makes us different and why thousands of patients across the country trust us with their care.

Real-Time Nurse Practitioner Approval

Every single Pure IV treatment is reviewed and approved by a licensed Nurse Practitioner in real time before your IV starts. This is not a checkbox. This is not something that happens hours later. A licensed medical professional reviews your health information and approves your specific treatment plan before the IV bag is hung. Most mobile IV companies in Knoxville skip this step entirely or use a generic questionnaire with no live review. That is not safe enough for us, and it should not be safe enough for you.

Free Good Faith Exam

Before every treatment, you will complete a quick Good Faith Exam (GFE). This is a fast medical review conducted by a licensed Nurse Practitioner or Medical Doctor. It is free, takes just a few minutes, and is valid for one full year. Once you complete your GFE, you can book treatments for 12 months without repeating it. No waiting rooms. No long clearance times. Just a quick review, and you are good to go.

Licensed Tennessee Registered Nurses

Every Pure IV treatment in Knoxville is administered by a licensed Registered Nurse or licensed Paramedic who is credentialed in the state of Tennessee. Our providers have extensive experience with IV therapy and follow strict clinical protocols. You are getting the same caliber of care you would receive in a hospital or emergency room, delivered in the comfort of your living room.

Same-Day Service, 7 Days a Week

When you feel terrible, you do not want to wait until tomorrow. Pure IV offers same-day mobile IV therapy in Knoxville with typical response times of 2 to 4 hours. Book online or call us at (629) 262-9109, and we will have a licensed provider at your door quickly. We are available every day of the week, including weekends and holidays.

No Travel Fees, No Hidden Charges

No travel fees. No waiting rooms. No hidden charges. The price you see on our website is the price you pay. We also accept HSA and FSA payments, so you can use your pre-tax healthcare dollars.

Physician-Owned and Operated

Pure IV operates under the medical direction of board-certified physicians and experienced Nurse Practitioners. Our leadership team includes ER doctors and clinical professionals who have built the company from the ground up with patient safety as the number one priority. This is not a side hustle. This is a real medical company with real medical oversight.

How Mobile IV Therapy Works in Knoxville

Getting mobile IV therapy in Knoxville is simple. Here is how it works in three easy steps.

Step 1:

Book Your Appointment

Choose your IV treatment and pick a time that works for you. You can book online 24 hours a day or call us at (629) 262-9109. Same-day appointments are available seven days a week. After booking, you will complete a short health questionnaire and a quick Good Faith Exam.

Step 2:

Your Provider Arrives

A licensed Registered Nurse or Paramedic arrives at your Knoxville location with all the equipment needed for your treatment. They will verify your identity, answer any questions you have, and review your treatment plan, which has already been approved by a licensed Nurse Practitioner in real time.

Step 3:

Relax and Feel Better

Sit back, relax, and let the IV do its work. Most treatments take just 30 to 45 minutes. Your provider stays with you during the entire treatment. Many people start feeling relief during or right after the session. Full effects are usually felt within a few hours.

Popular IV Treatments

Popular IV Therapy Treatments in Knoxville, TN

Pure IV offers over 30 IV therapy packages designed to help you recover, recharge, and feel your best. Every treatment is customizable with add-on vitamins, minerals, and medications. Here are some of the most popular IV treatments our Knoxville patients choose.

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Hangover IV

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    Knoxville knows how to have a good time. After a night out on the Old City strip, a UT tailgate at The Strip on Cumberland Avenue, or a bachelorette party on Gay Street, our Hangover IV is designed to get you back on your feet fast. This treatment includes IV hydration, electrolytes, B-complex vitamins, anti nausea medicine, and anti pain medicine to quickly relieve headache, nausea, fatigue, and dehydration.

Price: $275*

(*prices may vary per state)

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Myers Cocktail IV

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    The Myers Cocktail IV is our most popular package for overall hydration and wellness support. It includes a powerful blend of Vitamin C, Magnesium, B-Complex vitamins, and B12. This IV is great for Knoxville residents who want immune support, energy, and total body wellness. It is also a favorite among UT students during finals week and Knoxville professionals who need a midweek reset.

Price: $210*

(*prices may vary per state)

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Immune Boost IV

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    When cold and flu season rolls through East Tennessee, the Immune Boost IV is your best defense. Packed with high-dose Vitamin C, Zinc, and immune-supporting nutrients delivered directly into your bloodstream, this treatment helps your body fight off illness faster than oral supplements ever could. It is especially popular during fall and winter in Knoxville when the weather changes quickly.

Price: $210*

(*prices may vary per state)

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Athletic Performance IV

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    Knoxville is a city full of athletes. From UT student-athletes to weekend runners training for the Covenant Health Knoxville Marathon to hikers tackling trails in the Smokies, the Athletic Performance IV helps you recover faster, reduce muscle soreness, and rehydrate after intense physical activity. This package includes amino acids, B vitamins, electrolytes, and anti-inflammatory support.

Price: $235*

(*prices may vary per state)

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Migraine & Headache IV

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    If you suffer from migraines or chronic headaches, our Migraine IV can provide fast relief without a trip to the ER or urgent care. This treatment includes magnesium, B-complex vitamins, anti nausea medicine, and anti pain medicine to ease throbbing pain, reduce nausea, and help you get back to your day.

Price: $285*

(*prices may vary per state)

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NAD+

IV Therapy

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    NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell of your body that plays a role in energy production, cellular repair, and brain function. Our NAD+ IV Therapy is popular among Knoxville patients looking for anti-aging support, mental clarity, improved focus, and long-lasting energy. This is an advanced treatment that goes beyond basic hydration.

Price: Varies per dosage

(*prices may vary per state)

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Cold &

Flu IV

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    When a cold or stomach bug hits, the last thing you want to do is drag yourself to a clinic. Our Cold & Flu IV comes to you at home in Knoxville and delivers hydration, immune support, anti nausea medicine, and vitamins straight into your bloodstream. You skip the waiting room and start feeling better in the comfort of your own bed.

Price: $210*

(*prices may vary per state)

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Beauty &

Anti-Aging IV

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    Our Beauty IV is loaded with Glutathione (the master antioxidant), Biotin, Vitamin C, and B-Complex to support healthy skin, hair, and nails from the inside out. This treatment is a favorite among Knoxville patients who want to look and feel their best without expensive topical treatments.

Price: $255*

(*prices may vary per state)

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Food Poisoning & Stomach Bug IV

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    Nothing ruins your week like food poisoning or a stomach virus. Our Food Poisoning IV and Stomach Bug IV deliver rapid hydration, electrolyte replacement, anti nausea medicine, and anti heartburn medicine to help you stop vomiting, ease stomach cramps, and recover faster.

Price: $235*

(*prices may vary per state)

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GLP-1 & Weight Loss Medication Nausea IV

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    More and more Knoxville residents are using GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound for weight management. A common side effect is severe nausea. Our GLP-1 Nausea IV is specifically designed to combat the nausea, dehydration, and stomach discomfort that can come with these medications. It includes anti nausea medicine, anti heartburn medicine, hydration, and electrolyte replacement.

Price: $295*

(*prices may vary per state)

Customize Your IV with Add-On Vitamins and Medications

Every body is different. That is why every Pure IV treatment can be customized. You can add extra vitamins, minerals, and medications to your IV to target your specific needs. Here are some of the most popular add-ons our Knoxville patients choose.

  • Glutathione — The master antioxidant. Supports detox, skin health, and cellular repair.
  • NAD+ — Cellular energy and anti-aging support.
  • Biotin — Hair, skin, and nail health.
  • Vitamin C — Immune boost and antioxidant protection.
  • Magnesium — Muscle relaxation and migraine relief.
  • B12 — Metabolism, energy, and focus.
  • Zinc — Wound healing and immune support.
  • Vitamin D — Bone health and mood support.
  • Tri-Immune Boost — A combination of Glutathione, Vitamin C, and Zinc for maximum immune defense.
  • Anti Nausea Medicine — Fast relief from nausea and vomiting.
  • Anti Pain Medicine — Effective relief from headaches, body aches, and inflammation.
  • Anti Heartburn Medicine — Reduces stomach acid and relieves heartburn.
  • Amino Blend — Muscle recovery and tissue repair.

Areas We Serve in Knoxville and East Tennessee

Pure IV provides mobile IV therapy throughout Knoxville and surrounding communities in Knox County and East Tennessee. Our licensed nurses travel to you, wherever you are. Here are the areas and neighborhoods we serve.

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Downtown Knoxville & The Old City

We serve hotels, apartments, offices, and event venues in the heart of downtown Knoxville, including areas near Market Square, Gay Street, the Old City entertainment district, World’s Fair Park, the Knoxville Convention Center, and the Tennessee Theatre. Whether you are a tourist exploring downtown or a local recovering after a night out, we are just a call away.

University of Tennessee / Fort Sanders / The Strip

UT students, faculty, staff, and game-day visitors can get mobile IV therapy delivered right to their dorm, apartment, or tailgate area near Neyland Stadium. Our hangover IV, immune boost IV, and energy boost IV are especially popular during football season, finals week, and Greek life events.

West Knoxville & Farragut

West Knoxville and the Farragut community are two of the fastest-growing areas in Knox County. Families, professionals, and active adults in these neighborhoods choose Pure IV for convenience and quality care without the drive to a clinic. We serve neighborhoods along Kingston Pike, Pellissippi Parkway, and Turkey Creek.

North Knoxville & Fountain City

Fountain City and the neighborhoods along Broadway in North Knoxville are well within our service area. We bring mobile IV therapy directly to homes and businesses in this established Knoxville community.

South Knoxville & Island Home

South Knoxville, including the Island Home and Chapman Highway corridors, is a growing area with a mix of longtime residents and new development. Pure IV delivers to homes, apartments, and Airbnbs throughout South Knoxville.

East Knoxville & Parkridge

East Knoxville neighborhoods including Parkridge, Burlington, Five Points, and the Magnolia Avenue corridor are all served by Pure IV. We come to you so you can stay comfortable while you recover.

Bearden, Sequoyah Hills & Kingston Pike

These established West Knoxville neighborhoods are home to many of our most loyal patients. Whether you are in Sequoyah Hills along the river, in the Bearden shopping district, or anywhere along the Kingston Pike corridor, we will be at your door fast.

Surrounding Knox County and East Tennessee Communities

We also serve surrounding areas including Powell, Halls, Karns, Hardin Valley, Oak Ridge, Maryville, Alcoa, Lenoir City, Sevierville, and Gatlinburg. If you are within our Knoxville service area, we can come to you. Call us at (629) 262-9109 to confirm availability at your exact location.

Why People in Knoxville Need Mobile IV Therapy

Hot, Humid Summers Cause Dehydration

Knoxville summers are hot and humid, with temperatures regularly hitting the 90s from June through September. This kind of heat causes dehydration fast, especially if you are working outdoors, exercising, or spending the day at a festival. Our Dehydration IV replenishes fluids and electrolytes directly into your bloodstream for fast relief that water alone cannot match.

Proximity to the Great Smoky Mountains

Knoxville sits at the doorstep of the Great Smoky Mountains National Park, the most visited national park in the United States. Millions of tourists pass through Knoxville every year on their way to or from the Smokies. Hiking at higher elevations, even at Clingmans Dome (6,643 feet), can cause mild altitude-related symptoms including headaches, nausea, and fatigue. Our Altitude Sickness IV is designed to help with exactly that.

University of Tennessee Game Days and Events

Neyland Stadium holds over 100,000 fans on game day, making it one of the largest stadiums in the country. UT football weekends bring massive crowds, tailgating, late nights, and a lot of celebrating. The day after a big game is one of our busiest days in any college town. Our hangover IV and hydration IV help fans, students, and visitors bounce back quickly so they can enjoy the rest of their weekend.

Knoxville’s Festival and Event Scene

Knoxville hosts dozens of major events and festivals throughout the year, including the Big Ears Festival, the Dogwood Arts Festival, the Rossini Festival, the Covenant Health Knoxville Marathon, Boomsday, the Tennessee Valley Fair, the Big Kahuna Wing Festival, and many more. Whether you are running 26.2 miles, dancing all night at Big Ears, or spending a long day in the sun at World’s Fair Park, Pure IV helps you recover and rehydrate.

Growing Popularity of GLP-1 Weight Loss Medications

Medications like Ozempic, Wegovy, Mounjaro, and Zepbound are increasingly popular across Tennessee for weight management. A very common side effect is severe nausea and dehydration. Pure IV’s GLP-1 Nausea IV is specifically designed for this growing need and has become one of our fastest-growing treatments.

Busy Families, Students, and Professionals

Knoxville is growing. The metro area population is over 800,000, and Knox County alone has nearly 480,000 residents. Busy parents in Farragut, tech workers in Hardin Valley, college students at UT, and healthcare professionals at UT Medical Center all share one thing in common: they do not have time to sit in a waiting room when they are feeling run down. Pure IV brings the care to them.

Special IV Therapy Services Available in Knoxville

Group IV Therapy

Hosting a bachelorette party, bachelor weekend, corporate event, bridal party, or group outing in Knoxville? Pure IV offers group IV therapy with discounts for groups of 3 or more. We bring everything to your location and treat your entire group on-site.

Wedding & Bridal Party IV

Your wedding day should be perfect. Our Wedding & Bridal Party IV service helps brides, grooms, and wedding parties feel their best on the big day. We can treat the wedding party the morning of or help everyone recover the day after.

Corporate Wellness

Knoxville employers can boost team morale and productivity with corporate wellness IV therapy. We bring mobile IV treatments directly to your office, warehouse, or job site. This is a popular option for companies during flu season, high-stress periods, and team wellness events.

Kids IV Therapy (Ages 3+)

When your child is dehydrated from a stomach bug or illness and cannot keep fluids down, our Kids IV Therapy can help. We send specialized, pediatric-experienced providers to your Knoxville home to administer IV hydration in a calm, comfortable setting. Important note: same-day service is often possible, but we dispatch pediatric-experienced providers for these calls, so timing may vary.

Pure IV Pricing

IV Therapy Pricing in Knoxville, TN

Pure IV offers transparent pricing with no hidden fees and no travel charges. Below are some of our most popular IV therapy packages. For our complete menu of 30+ packages, visit our IV Packages & Pricing page.

IV therapy packages start at $130 and prices may vary by location. No travel fees. No waiting rooms. No hidden charges. We accept all major credit cards, cash, and HSA/FSA payments.

For our full menu of 30+ packages with current pricing, visit our IV Packages & Pricing page.

Client Reviews

What Are People Saying About Pure IV?

FAQ's

Frequently Asked Questions About IV Therapy in Knoxville

  • Is mobile IV therapy in Knoxville safe?

    Yes. Every Pure IV treatment is administered by a licensed Tennessee Registered Nurse or Paramedic. Your treatment is reviewed and approved in real time by a licensed Nurse Practitioner before your IV starts. We follow strict clinical protocols and only use hospital-grade IV supplies.

  • How fast can I get a mobile IV in Knoxville?

    We offer same-day service with typical response times of 2 to 4 hours. In many cases, we can be at your door even faster. Book online or call (629) 262-9109.

  • What is a Good Faith Exam?

    A Good Faith Exam (GFE) is a quick medical review conducted by a licensed Nurse Practitioner or Medical Doctor before your first IV treatment. It is free, takes just a few minutes, and is valid for one full year. This ensures your safety and is required before any IV therapy can be administered.

  • Do I need a prescription for IV therapy?

    No prescription is needed. Our Nurse Practitioners review and approve every treatment in real time through our Good Faith Exam process.

  • How long does a mobile IV treatment take?

    Most treatments take 30 to 45 minutes from start to finish. Your provider stays with you the entire time.

  • Where can I receive my IV in Knoxville?

    Anywhere that is comfortable for you. We come to your home, apartment, hotel room, Airbnb, office, dorm, or event space anywhere in the Knoxville metro area.

  • Do you charge a travel fee in Knoxville?

    No. Pure IV does not charge travel fees and there are no waiting rooms. We come to you. The price you see is the price you pay.

  • Do you accept insurance, HSA, or FSA?

    Most mobile IV therapy services are not covered by insurance. However, we do accept HSA (Health Savings Account) and FSA (Flexible Spending Account) payments. We provide detailed receipts for easy reimbursement submission.

  • How soon will I feel better after my IV?

    Many patients start feeling relief during the treatment or within 30 minutes after. Full effects are typically felt within a few hours. Results vary depending on your symptoms and the treatment you receive.

  • Can I get IV therapy for my kids in Knoxville?

    Yes. Pure IV provides pediatric IV therapy for children ages 3 and up. We dispatch specialized, pediatric-experienced providers to your home. Pediatric calls are carefully scheduled to ensure the right provider is available.

  • What areas near Knoxville do you serve?

    We serve the entire Knoxville metro area including downtown Knoxville, West Knoxville, Farragut, Bearden, North Knoxville, South Knoxville, East Knoxville, the UT campus, Powell, Halls, Karns, Hardin Valley, and surrounding communities. Call us to confirm availability at your specific location.

  • What makes Pure IV different from other IV therapy companies in Knoxville?

    Pure IV is physician-owned and operated. We provide real-time Nurse Practitioner approval before every treatment, same-day service, no travel fees, transparent pricing, and licensed Tennessee Registered Nurses. We have served over 25,000 patients nationwide and are one of the largest mobile IV therapy companies in the country.

Book Your Mobile IV Therapy in Knoxville Today

Do not let dehydration, fatigue, or illness slow you down. Pure IV delivers fast, professional mobile IV therapy to your door anywhere in the Knoxville metro area. With same-day service, real-time Nurse Practitioner approval, and licensed Tennessee Registered Nurses, you are in the best hands.

Ready to feel better? 

to schedule your in-home IV therapy appointment today.

Pure IV – Knoxville’s Most Trusted Mobile IV Therapy Provider

Serving Downtown Knoxville, West Knoxville, Farragut, Bearden, Sequoyah Hills, North Knoxville, Fountain City, South Knoxville, East Knoxville, the University of Tennessee, Powell, Halls, Karns, Hardin Valley, and all of Knox County.

Same-day Appointments Available    No travel fees     No Waiting Rooms

Licensed Tennessee RNs   Real-time NP Approval  HSA & FSA Accepted